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muTarget
connect mutation status to gene expression changes in solid tumours
Running parameters
Selected gene(s):
TTK
Tumor type(s):
Lung Adenocarcinoma
Mutation type:
All somatic mutations
Mutation filter:
Off
- exclude patients with mutation in:
-
- include patients with mutation in:
-
P value cutoff:
0.01
Fold change cutoff:
1.44
FDR cutoff:
No FDR filter
Exclude genes with a mean expression below 100:
Yes
Generate table for:
All significant genes
Show plot for:
top 5
Gene ontology:
Off
RESULTS
Lung Adenocarcinoma
Expression of
Mean mutant (n=17)
Mean wild (n=491)
FC (mutant/wild)
Direction
p-value
ZBED3
245
477.45
1.96
down
1.08e-04
NFIA
483.06
995.96
2.04
down
1.80e-04
TMEM200B
255.18
138.87
1.84
up
5.72e-04
LRTOMT
176.82
285.03
1.61
down
6.18e-04
PABPC1
63866
42139.6
1.52
up
6.99e-04
CYP39A1
56.59
142.51
2.5
down
7.69e-04
TSPAN8
807.18
2565.46
3.23
down
8.76e-04
MEIS2
193.76
332.58
1.72
down
9.76e-04
FBXO17
341.47
209.63
1.63
up
1.03e-03
IFT172
529.59
830.63
1.56
down
1.05e-03
Download results table for all significant genes
Download plots as pdf
