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mu
Target
connect mutation status to gene expression changes in solid tumours
Running parameters
Selected gene:
SKP2
Tumor type(s):
Lung Adenocarcinoma
Mutation type:
All somatic mutations
Mutation prevalence at least:
2%
Mutation filter:
Off
- exclude patients with mutations in:
-
- include patients with mutations in:
-
P value cutoff:
0.01
Fold change cutoff:
1.44
FDR cutoff:
No FDR filter
Show plot for:
top 5
Gene ontology:
Off
RESULTS
Lung Adenocarcinoma
Mutation of
Mean expression (mutant)
Mean expression (wild)
Number of mutant
Number of wild
FC (mutant/wild)
Direction
p-value
TP53
781.49
399.22
241
267
1.96
up
2.15e-24
KRAS
415.76
642.66
139
369
1.54
down
3.95e-08
TTN
713.64
471.35
229
279
1.51
up
3.68e-07
COL5A2
1004.58
534.29
50
458
1.88
up
7.27e-07
RB1
1017.17
553.17
30
478
1.84
up
1.75e-06
SORCS1
901.7
537.57
60
448
1.68
up
2.96e-06
FBN2
890.53
527.73
74
434
1.69
up
5.13e-06
PIK3AP1
1575.44
544.03
18
490
2.9
up
1.14e-05
DSCAM
1040.4
539.13
42
466
1.93
up
1.25e-05
CSMD2
894.43
530.42
70
438
1.69
up
1.27e-05
Download results table for all significant genes
Download plots as pdf