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muTarget
connect mutation status to gene expression changes in solid tumours
Running parameters
Selected gene:
KIF11
Tumor type(s):
Breast cancer (TCGA)
Mutation type:
All somatic mutations
Mutation prevalence at least:
2%
Mutation filter:
Off
- exclude patients with mutations in:
-
- include patients with mutations in:
-
P value cutoff:
0.01
Fold change cutoff:
1.44
FDR cutoff:
No FDR filter
Show plot for:
top 10
Gene ontology:
Off
RESULTS
Breast cancer
Mutation of
Mean expression (mutant)
Mean expression (wild)
Number of mutant
Number of wild
FC (mutant/wild)
Direction
p-value
TP53
1523.05
940.74
336
643
1.62
up
8.57e-33
CDH1
776.22
1200.39
138
841
1.54
down
1.21e-10
MAP3K1
810.8
1169.94
80
899
1.45
down
1.38e-05
DYNC2H1
1924.72
1114.1
32
947
1.73
up
2.12e-05
RELN
1713.19
1121.25
32
947
1.53
up
4.17e-05
RB1
1798.43
1124.77
23
956
1.6
up
8.17e-04
FAT3
1637.23
1117.23
44
935
1.47
up
8.86e-04
PEG3
1792.54
1124.21
24
955
1.59
up
1.22e-03
Download results table for all significant genes
Download plots as pdf