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muTarget
connect mutation status to gene expression changes in solid tumours
Running parameters
Selected gene(s):
CREBBP
Tumor type(s):
Breast cancer (TCGA)
Mutation type:
All somatic mutations
Mutation filter:
Off
- exclude patients with mutation in:
-
- include patients with mutation in:
-
P value cutoff:
0.01
Fold change cutoff:
1.44
FDR cutoff:
No FDR filter
Exclude genes with a mean expression below 100:
Yes
Generate table for:
All significant genes
Show plot for:
top 5
Gene ontology:
Off
RESULTS
Breast cancer
Expression of
Mean mutant (n=20)
Mean wild (n=959)
FC (mutant/wild)
Direction
p-value
KCTD6
219.45
558.85
2.56
down
1.15e-05
CYP2A7
0.65
560.64
Inf
down
3.37e-05
PLOD1
11834.05
5037.63
2.35
up
4.79e-05
MAP2K3
1775
1236.23
1.44
up
6.07e-05
PPARD
2016.95
1340.62
1.5
up
7.52e-05
TTC6
156.4
471.62
3.03
down
7.63e-05
ACVR1B
1099.45
1675.06
1.52
down
8.75e-05
PAPSS1
4478.05
2929.07
1.53
up
9.05e-05
ACOX2
153.85
696.82
4.55
down
1.05e-04
HAPLN3
2343.1
705.88
3.32
up
1.06e-04
Download results table for all significant genes
Download plots as pdf